Hypothalamo-pituitary-adrenal function in patients on long-term adrenocorticotrophin therapy.
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چکیده
منابع مشابه
Hypothalamo-pituitary-adrenal function in patients on long-term adrenocorticotrophin therapy.
Adrenocorticotrophic hormone (ACTH) is of value in the treatment of a number of diseases which respond to corticosteroid therapy, and has been preferred to corticosteroids themselves by several clinicians on the grounds that side-effects are fewer and withdrawal easier (Savage, Copeman, Chapman, Wells, and Treadwell, 1962), that there is a better clinical response in rheumatoid arthritis (West,...
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Sixteen patients with intrinsic non-atopic asthma with persistent wheezing who had never been treated with corticosteroids showed normal adrenocortical responses to prolonged stimulation with Tetracosactin Depot. In a subgroup of six patients the hypothalamo-pituitary-adrenal (HPA) response to a standard insulin stress test was normal. It is concluded that impaired responsiveness of the HPA axi...
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To observe the influence of thyroid hormone therapy on hypothalamo-pituitary-adrenal (HPA) axis, a group of 14 athyreotic women due to thyroid cancer treatment were studied before and after thyroid suppression therapy with thyroxine (T4). Changes in plasma adrenocorticotropin (ACTH) and cortisol levels in response to human corticotropin-releasing hormone (hCRH; 100µg, i.v.) were estimated under...
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The hypothalamo-pituitary-adrenal (HPA) axis is modulated by sex hormones. Few data exist on the relation between acute estrogen deficit and HPA axis response to corticotropin-releasing hormone (CRH). The effects of a sudden drop in estradiol levels on basal and CRH-stimulated levels of ACTH, cortisol, testosterone, androstenedione and 17-hydroxyprogesterone (17-OHP) were assessed in nine preme...
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BACKGROUND The hypothalamo-pituitary-adrenal (HPA) axis modulates the inflammatory response during sepsis. Macrophage migration inhibitory factor (MIF), which counteracts the anti-inflammatory activity of glucocorticoid (GC), is one of the mediators of the development of inflammation. An inflammatory imbalance involving GC and MIF might be the cause or result of adrenal insufficiency. Our objec...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1968
ISSN: 0003-4967
DOI: 10.1136/ard.27.1.7